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应用双抗体夹心ELISA法检测170例子宫肌瘤、子宫颈癌、卵巢癌、绒癌等患者血清白细胞介素2受体(sIL-2R)水平,结果表明,子宫颈癌、卵巢癌及绒癌患者血清sIL-2R水平明显高于子宫肌瘤及疾病对照组(P<0.001)。妇科恶性肿瘤患者经手术切除及放疗、化疗后血清sIL-2R水平明显下降(P<0.001)。提示检测血清sIL-2R水平对妇科良、恶性肿瘤的鉴别诊断和疗效观察有意义。
Serum interleukin 2 receptor (sIL-2R) levels in 170 cases of uterine fibroids, cervical cancer, ovarian cancer and choriocarcinoma were detected by double antibody sandwich ELISA. The results showed that cervical cancer, ovarian cancer and choriocarcinoma Serum sIL-2R levels were significantly higher in patients with uterine fibroids and disease control (P <0.001). Patients with gynecologic malignancies underwent surgical resection and radiotherapy, and the level of serum sIL-2R was significantly decreased after chemotherapy (P <0.001). Prompt detection of serum sIL-2R levels of gynecological benign and malignant tumors of the differential diagnosis and efficacy of meaningful.