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为探讨中耳炎病理过程中潴留渗出液的病理转归和肉芽组织的形成机理。方法:对美国明尼苏达大学颞骨病理实验室306耳各型伴渗出液的中耳炎颞骨连续切片进行了光镜组织病理学观察研究。结果:在中耳炎从早期病理阶段向更晚期病理阶段进展的过程中,渗出液的性质和潴困状态处于动态变化当中;肉芽组织由两种方式的粘膜下成纤维细胞增生而成;潴留渗出液的吸收、机化与肉芽组织形成是同时发生在同一区域的同一病理过程中。结论;肉芽组织仅在渗出液积存和吸收的地方形成;炎性渗出液在中耳停留时间越长,形成肉芽组织的机会就越多,为防止早期伴渗出液的中耳炎向慢性阶段发展,在肉芽组织形成之前彻底引流中耳各处的积液至关重要。
In order to explore the pathogenesis of otitis externa in pathological process of otitis media and the formation mechanism of granulation tissue. Methods: The histopathology of the temporal bone of otitis media with 306 exudate in the temporal bone histopathology laboratory of the University of Minnesota was studied by light microscopy. RESULTS: During the progression of otitis media from early pathology to more advanced pathology, the nature of exudate and the state of retention were in a dynamic state; granulation tissue consisted of two forms of submucosal fibroblasts; retention retention Absorption of fluid, mechanization and granulation tissue formation occurs simultaneously in the same area in the same pathological process. Conclusions: Granulation tissue is formed only in the area where exudate accumulates and absorbs. The longer the inflammatory exudate stays in the middle ear, the more chances of forming granulation tissue. In order to prevent the early stage of otitis media with exudate, Development, complete drainage of granulation tissue throughout the middle ear effusion is essential.