论文部分内容阅读
目的考察不同批次益肝散中钒(V)、铬(Cr)、铁(Fe)、钴(Co)、镍(Ni)、铜(Cu)、砷(As)、硒(Se)、钼(Mo)、镉(Cd)、汞(Hg)和铅(Pb)金属元素的含量。方法采用湿法消解法消解样品,以115In为内标,用电感耦合等离子质谱法同时测定益肝散中钒、铬、铁、钴、镍、铜、砷、硒、钼、镉、汞和铅金属元素的含量。结果检测的12种元素线性关系良好,相关系数r≥0.999 2,各元素的检出限为0.038~0.537μg·L-1,回收率为100.0%~104.7%,RSD≤4.4%,重复性和精密度的RSD值均≤5%。结论该方法适用于益肝散的微量元素及重金属限量控制。可考虑应用于其他中药材的检测。
Objective To investigate the effects of different batches of Yigan powder on the contents of vanadium, chromium, iron, cobalt, nickel, copper, arsenic, selenium, Mo, Cd, Hg and Pb. Methods The samples were digested by wet digestion method and 115In was used as the internal standard. Simultaneous determination of vanadium, chromium, iron, cobalt, nickel, copper, arsenic, selenium, molybdenum, cadmium and mercury in Yigan Powder by inductively coupled plasma mass spectrometry Lead metal content. Results The 12 elements tested showed a good linear relationship with a correlation coefficient of r ≥ 0.9999. The detection limits were 0.038-0.537 μg · L-1. The recoveries were 100.0% -104.7%, RSD ≤ 4.4% Precision RSD values are ≤ 5%. Conclusion This method is applicable to the trace elements of Yigan Powder and the limited control of heavy metals. Can be considered applied to the detection of other Chinese herbal medicines.