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本研究报告了河北省 1996～ 1998年AFP病例中脊髓灰质炎疫苗病毒、非脊髓灰质炎肠道病毒 (NPEV)感染的流行病学和临床特征 ,显示NPEV感染有明显的夏秋季感染高峰 ,感染主要发生在小年龄组人群 :AFP病例中NPEV感染者作为一组病例 ,一般不会与脊灰诊断相混淆 ,在有明确诊断的病例中以格林巴利综合征为最多 ,但资料同时也显示有 38%的NPEV感染者有与脊灰相类似的麻痹时发热和急速进行性麻痹的临床表现 ,5 %的NPEV感染者除上述症状外 ,还在发病后60天残留麻痹。分离到脊髓灰质炎疫苗病毒的病例 ,更具有与野病毒感染相似的临床表现 ,麻痹后恢复慢 ,有较高的麻痹残留率 ,达 2 0 9% ,但无明显的季节性分布
This study reports the epidemiological and clinical features of poliomyelitis A (AIV) and non-polio enterovirus (AIV) infections in AFP cases from 1996 to 1998 in Hebei Province. It shows that NPEV infection has a significant peak in summer and autumn infection, Mainly occurs in the younger age group: NPEV infection in AFP cases as a group of patients, generally not be confused with polio diagnosis, in patients with a clear diagnosis of Guillain-Barre syndrome is the most, but the data also showed Thirty-eight percent of NPEV-infected patients have clinical manifestations of fever and rapid paralysis at paralysis similar to those of polio, and 5% of NPEV-infected patients have residual paralysis 60 days after onset in addition to the above symptoms. Isolated cases of poliovirus, but also has a similar clinical manifestations with wild-type virus infection, slow recovery after paralysis, a higher paralysis residual rate, up to 209%, but no significant seasonal distribution