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Conversion of cell fate is not only an essential biological question,but also has great clinical values.In early 1950s,cellular reprogramming was frst achieved using the technique of somatic cell nuclear transfer(SCNT),which transferred the nuclear of somatic cells into an enucleated oocyte,thus converted the mature somatic cells into pluripotent state.Using this technique
Conversion of cell fate is not only an essential biological question, but also has great clinical values. In early 1950s, cellular reprogramming was frst achieved using the technique of somatic cell nuclear transfer (SCNT), which transferred the nuclear of somatic cells into an enucleated oocyte, thus converted the mature somatic cells into pluripotent state. Using this technique