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目的评价应用丙泊酚和芬太尼麻醉实施胃镜检查的效果及安全性。方法选40例患者为观察组(丙泊酚联合芬太尼静脉麻醉),同期对照组(常规操做)40例,对检查过程中血压、心率、血氧饱和度及检查成功率、检查反应进行观察分析,并在检查后询问患者的感受。结果与对照组比较,观察组在胃镜检查中流涎、恶心呕吐、躁动、咳嗽等不适明显减少(P<0.05),检查后难以忍受和不舒适的感觉明显减少(P<0.05),无不适和愿意再次接受胃镜检查的患者明显增多(P<0.05)。观察组患者检查前收缩压平均为(126.8±18.4)mmHg(1mmHg=0.133kPa),检查中为(115.8±16.4)mmHg,差异有统计学意义(P<0.05),舒张压在检查中有下降但差异无统计学意义(P>0.05);对照组收缩压在检查前平均为(112.8±12.5)mmHg,检查中为(122.6±16.8)mmHg,差异有统计学意义(P<0.05),对照组舒张压在检查前平均为(65.3±9.6)mmHg,检查中为(70.9±10.3)mmHg,差异有统计学意义(P<0.05)。对照组心率检查前平均为(74.0±6.5)次/min,检查中为(82.5±9.9)次/min,差异有统计学意义(P<0.05)。血氧饱和度值变化均无统计学差异。检查成功率、操作时间两组相比差异无统计学意义(P>0.05)。结论丙泊酚联合芬太尼静脉麻醉,进行胃镜检查是安全、舒适、无痛苦的方法。
Objective To evaluate the efficacy and safety of gastroscopy with propofol and fentanyl anesthesia. Methods 40 patients were selected as the observation group (propofol combined with fentanyl intravenous anesthesia), the same period in the control group (routine operation) 40 cases, check the course of blood pressure, heart rate, oxygen saturation and the success rate of the test, check the reaction Observation and analysis, and after the test asked the feelings of patients. Results Compared with the control group, the appetite, nausea, vomiting, restlessness, cough and other discomfort in the observation group were significantly decreased (P <0.05), and the unbearable and uncomfortable feeling after the examination was significantly reduced (P <0.05) Patients who were willing to undergo gastroscopy again significantly increased (P <0.05). The mean systolic blood pressure before the test in the observation group was (126.8 ± 18.4) mmHg (1mmHg = 0.133kPa), with a mean value of (115.8 ± 16.4) mmHg in the observation group (P <0.05) But the difference was not statistically significant (P> 0.05). The systolic blood pressure of the control group was (112.8 ± 12.5) mmHg before the test and was (122.6 ± 16.8) mmHg, the difference was statistically significant (P <0.05) The average diastolic blood pressure before the test was (65.3 ± 9.6) mmHg, and the test was (70.9 ± 10.3) mmHg, the difference was statistically significant (P <0.05). The average heart rate before the test in the control group was (74.0 ± 6.5) times / min and the test was (82.5 ± 9.9) times / min, the difference was statistically significant (P <0.05). There was no significant difference in oxygen saturation value. There was no significant difference in success rate and operation time between the two groups (P> 0.05). Conclusions Propofol combined with intravenous fentanyl for gastroscopy is a safe, comfortable and painless method.