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在心肌梗塞(MI)后生化改变的研究中,发现儿茶酚胺(CA)起着极为重要的作用。它不仅影响体内激素的分泌和代谢过程,而且是触发体内各种生化改变的最重要机制。本文就MI后体内的CA变化及其变化对有关的激素代谢性反应、心梗范围、心律失常作一简要介绍, 一、MI后体内CA的变化动物实验和临床观察均表明MI时血、尿液中CA含量增高,且与MI的严重程度有关。Griffiths采用定量抽取血样的方法,连续测定了MI病人24小时体内CA含量的变化,发现去甲肾上腺素(NE)升高为对照值的16倍以上,肾上腺素(EP)达5倍以上。MI时血循环中EP和NE是从肾
In studies of biochemical changes following myocardial infarction (MI), catecholamines (CA) were found to play an extremely important role. It not only affects hormone secretion and metabolism in the body, but also triggers the most important mechanism of various biochemical changes in the body. This article on MI in vivo CA changes and changes in the relevant hormone metabolism, myocardial infarction range, arrhythmia make a brief introduction, one, MI in vivo CA animal experiments and clinical observations have shown that when MI blood, urine CA content in the fluid increased, and the severity of MI. Griffiths continuously measured changes in CA content within 24 hours of patients with MI by quantitative blood sampling and found that norepinephrine (NE) increased more than 16-fold in the control and epinephrine (EP) by more than 5-fold. EP and NE in the blood circulation are from the kidneys at MI