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目的观察蔗糖铁注射液治疗缺铁性贫血(IDA)的临床疗效,并观察不良反应的发生情况。方法将自2008年10月至2010年10月我科收治的57例IDA患者随机分为观察组30例和对照组27例,观察组给予蔗糖铁注射液静脉滴注,对照组给予琥珀酸亚铁口服,总疗程均为8周,治疗后测定血红蛋白(Hb)和血清铁蛋白(SF),比较两组的临床疗效并观察不良反应的发生情况。结果观察组和治疗组治疗后总有效率间的差异无统计学意义(P>0.05);但是观察组治愈率明显优于对照组,差异有统计学意义(P<0.05);并且观察组Hb和SF指标改善情况亦明显优于对照组,差异有统计学意义(P<0.05);观察组不良反应的发生率仅为3.33%,明显低于对照组(29.6%)差异有统计学意义(P<0.05)。结论蔗糖铁注射液治疗IDA疗效显著,耐受性好,不良反应少。
Objective To observe the clinical efficacy of sucrose iron injection in the treatment of iron deficiency anemia (IDA) and to observe the incidence of adverse reactions. Methods Fifty-seven IDA patients admitted to our department from October 2008 to October 2010 were randomly divided into observation group (n = 30) and control group (n = 27). The observation group received intravenous infusion of sucrose iron injection and the control group received subcutaneous succinic acid Oral administration of iron, the total course of treatment were 8 weeks after treatment, hemoglobin (Hb) and serum ferritin (SF) were measured, the clinical efficacy and the incidence of adverse reactions were observed. Results There was no significant difference in the total effective rate between the observation group and the treatment group (P> 0.05). However, the cure rate of the observation group was significantly better than that of the control group (P <0.05). The Hb (P <0.05). The incidence of adverse reactions in the observation group was only 3.33%, which was significantly lower than that in the control group (29.6%) (P <0.05). The difference was statistically significant (P < P <0.05). Conclusion Sucrose iron injection is effective in treating IDA with good tolerance and few adverse reactions.