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肝硬化合并食管胃底曲张静脉破裂大出血是一种常见的、需采取紧急抢救措施的急症。在美国,肝硬化已成为65岁以下人群第5位的致死原因。首次出血死亡率即可高达60%,首次出血的存活者中20%～50%在1周内、50%～80%在1～2年内将再次出血。出血不仅可引起休克,还可并发和加重腹水,可导致肝性脑病、严重感染、肝肾综合征和肝功能衰竭,病人迅速死亡,其危急性和严重性并不亚于大血管破裂的创
Cirrhosis complicated with esophageal variceal bleeding is a common and urgent emergency requiring emergency treatment. In the United States, cirrhosis has become the fifth leading cause of death in people under the age of 65. The first bleeding mortality rate can be as high as 60% of the first bleeding survivors in 20% to 50% within 1 week, 50% to 80% in 1 to 2 years will be bleeding again. Bleeding can not only cause shock, but also complicated with and concurrent with ascites, can lead to hepatic encephalopathy, severe infection, hepatorenal syndrome and liver failure, rapid death of patients, their risk and severity of no less than a large vessel rupture