论文部分内容阅读
目的:探讨阴道细胞学作为术前预测子宫内膜癌患者预后的价值。方法:对103例子宫内膜癌的术前阴道细胞学检查结果与手术病理发现进行对比分析。结果:阴道细胞学正常68例(66.1%)、可疑9例(8.7%)、恶性26例(25.2%)。阴道细胞学与组织学类型、肿瘤分化程度、手术分期、宫颈及盆腔淋巴结转移等明显相关(P<0.05)。恶性阴道细胞学多见于非宫内膜样腺癌、低分化、晚期、宫颈及盆腔淋巴结转移者,其盆腔淋巴结转移的发生率比正常阴道细胞学者高6.2倍。阴道细胞学与子宫肌层浸润深度、附件转移、大网膜转移和腹腔细胞学阳性之间无明显关系(P>0.05)。结论:恶性阴道细胞学可望作为预测子宫内膜癌子宫外转移的指标,是一个不利预后因素。
Objective: To investigate the value of vaginal cytology as a predictor of prognosis in patients with endometrial cancer before surgery. Methods: The preoperative vaginal cytology results of 103 cases of endometrial cancer were compared with the surgical pathological findings. Results: The vaginal cytology was normal in 68 cases (66.1%), suspicious in 9 cases (8.7%), and malignant in 26 cases (25.2%). Vaginal cytology was significantly associated with histological type, tumor differentiation, surgical staging, cervical and pelvic lymph node metastasis (P<0.05). Malignant vaginal cytology is more common in non-endometrioid adenocarcinoma, poorly differentiated, advanced, cervical, and pelvic lymph node metastases. The incidence of pelvic lymph node metastasis is 6.2 times higher than that of normal vaginal cytologists. There was no significant relationship between vaginal cytology and myometrial infiltration depth, attachment metastasis, omental metastasis, and peritoneal cytology positive (P>0.05). Conclusion: Malignant vaginal cytology is expected to be an indicator of extrauterine metastasis in endometrial cancer and is an unfavorable prognostic factor.