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目的探讨在冠心病伴高血脂患者治疗中应用阿托伐他汀调血脂的临床价值。方法 84例冠心病伴高血脂患者进行研究,均给予阿托伐他汀连续用药治疗3个月。复查血脂情况,比较患者用药治疗前后血脂变化情况,统计临床疗效及药物不良反应情况。结果 84例患者临床总有效率为97.62%。治疗后患者体内血脂得到明显改善,其中甘油三酯(TG)、总胆固醇(TC)与低密度脂蛋白胆固醇(LDL-C)均有不同程度降低,高密度脂蛋白胆固醇(HDL-C)较治疗前明显升高(P<0.05);4例(4.76%)患者出现不良反应,对症治疗后可明显改善。结论在冠心病伴高血脂患者的治疗中应用阿托伐他汀进行调脂治疗,可取得较好的疗效,且安全有效,值得临床应用。
Objective To investigate the clinical value of atorvastatin on blood lipid in the treatment of patients with coronary heart disease and hyperlipidemia. Methods 84 cases of coronary heart disease with hyperlipidemia were studied, were given atorvastatin continuous medication for 3 months. Review the lipid status, compare the changes of blood lipid in patients before and after treatment, statistics of clinical efficacy and adverse drug reactions. Results The total effective rate of 84 patients was 97.62%. After treatment, the blood lipid of patients was significantly improved, including triglyceride (TG), total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) were reduced to varying degrees, high density lipoprotein cholesterol (HDL-C) There was a significant increase before treatment (P <0.05); 4 patients (4.76%) had adverse reactions and could be significantly improved after symptomatic treatment. Conclusions In the treatment of coronary heart disease with hyperlipidemia, atorvastatin is used in the treatment of lipid-lowering therapy, which can achieve better curative effect and is safe and effective, which is worthy of clinical application.