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急性肿瘤细胞溶解综合征(ATLS)是儿童淋巴系统恶性肿瘤化疗期间最常见及紧急的并发症,为肿瘤细胞对化疗药物敏感,大量溶解并破坏,释放其内容物引起的高血钾、高血磷、高尿酸及低钙血症等一系列电解质紊乱。病情进展快常引发心律失常及急性肾衰竭,有时未能及时透析而死亡。ATLS常发生于化疗的第1～3天,而一些生长快的恶性肿瘤,由于局部缺血低氧,
Acute neoplastic cell lysis syndrome (ATLS) is the most common and urgent complication of chemotherapy in childhood lymphatic system malignancies, which is sensitive to chemotherapeutic drugs, dissolves and destroys the tumor cells in a large amount, releases the contents of hyperkalemia, hyperkalemia Phosphorus, hyperuricemia and hypocalcemia and a series of electrolyte disorders. Rapid progression of the disease arrhythmia and acute renal failure, and sometimes failed to timely dialysis and died. ATLS often occurs in the first 1 to 3 days of chemotherapy, and some fast-growing malignant tumors, due to ischemia and hypoxia,