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酚妥拉明是常用的α受体阻滞剂,其临床应用日益广泛。本文就该药治疗慢性肺心病心力衰竭(下称肺心病心衰)的效果作一评价。一、治疗脑心病心衰的理论基础肺心病心衰应用洋地黄类制剂时,由于病人严重缺氧、感染及水、电解质与酸碱平衡失调,心肌对洋地黄的耐受性明显减低,故易诱发心律失常;若应用利尿剂,则由于病人常存在水、电解质与酸碱平衡失调,易致病情复杂化。因此,近年来已将血管扩张剂用于肺心病心衰治疗。其作用机理:①
Phentolamine is a commonly used alpha-blocker, its clinical application is increasingly widespread. This article on the drug treatment of chronic cor pulmonale heart failure (hereinafter referred to as cor pulmonale heart failure) to make an evaluation of the effect. First, the theoretical basis for the treatment of heart failure of heart disease Cor Pulmonale Heart failure application of digitalis preparations, the patient due to severe hypoxia, infection and water, electrolyte and acid-base balance disorders, myocardial tolerance to digitalis significantly reduced, so Easy to induce arrhythmia; if the use of diuretics, then the patient often exists in water, electrolytes and acid-base balance disorders, easy to cause complications. Therefore, in recent years vasodilators have been used for the treatment of heart failure of pulmonary heart disease. The mechanism of action: ①