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目的:探讨老年颈内动脉系统急性脑梗死动脉溶栓的疗效。方法:对我院老年科收治的63例老年颈内动脉系统急性脑梗死随机分为股动脉组以及颈动脉组,其中股动脉组患者30例,对其采用经皮股动脉穿刺微导管介入尿激酶溶栓治疗,颈动脉组患者33例,对其采用经皮患侧颈动脉穿刺尿激酶溶栓治疗。结果:对两组患者治疗前、术后2h以及术后30d采用NIHSS评分比较,两组患者NIHSS评分在术后2h及术后30d均较术前有明显改善(P<0.05);对两组患者治疗相关情况比较,股动脉组患者术后2h血管再通率明显高于颈动脉组(P<0.05),两组颅内出血率未显示出统计学差异性;对两组患者术后30d牛津残障OHS评分、BI指数比较,股动脉组患者明显优于颈动脉组(P<0.05)。结论:对老年急性脑梗死患者采用经皮股动脉穿刺微导管介入或采用经皮患侧颈动脉穿刺尿激酶溶栓治疗,均可有效改善患者预后,提高患者的临床疗效,两组相比较,股动脉组更能显示出优良的治疗率。
Objective: To investigate the effect of arterial thrombolysis in elderly patients with acute cerebral infarction of the internal carotid artery. Methods: A total of 63 elderly patients with acute cerebral infarction of the internal carotid artery were randomly divided into femoral artery group and carotid artery group, of which 30 patients in the femoral artery group were treated with percutaneous femoral artery catheterization Thrombolytic therapy of kinases, 33 cases of carotid artery group, percutaneous ipsilateral carotid artery embolization urokinase thrombolytic therapy. Results: The NIHSS scores of two groups before and after treatment, 2h and 30d after operation were significantly improved at 2h and 30d after operation (P <0.05) Compared with the treatment of patients, the recanalization rate of the femoral artery group at 2h after operation was significantly higher than that of the carotid artery group (P <0.05), and the intracranial hemorrhage rate did not show statistical difference between the two groups. On the 30th postoperative day, Disability OHS score and BI index were significantly higher in the femoral artery group than in the carotid artery group (P <0.05). Conclusion: The intervention of percutaneous femoral artery catheterization or percutaneous ipsilateral urokinase thrombolysis in elderly patients with acute cerebral infarction can effectively improve the prognosis of patients and improve the clinical efficacy. Compared with the control group, Femoral artery group can show better treatment rate.