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高血压病发展到一定阶段,血压不再依赖于高血压的原始病因,而被几个致病环节所支配,占主导地位的就是高血压蛋白原酶—血管紧张素—醛固酮系统,其中醛固酮是这个系统中最主要的激素。目前尚未能发现特异性醛固酮抑制剂,全切、次全切除肾上腺副作用又多,因此,人们寻找增加醛固酮代谢的方法来降低血压。肝脏对致高血压因子有灭活能力,已经知道,血液经肝脏转流一次,醛固酮被灭活90％—95％,高血压蛋白原酶被灭活20％—30％,有人作过实验性手术研究,目的是利用肝脏来消除由缺血肾所分泌的加压物质,并已证明肾静脉、肾上腺静脉血“门脉化”后肝机能及肝结构未受破坏。
Hypertension to a certain stage of development, blood pressure is no longer dependent on the original etiology of hypertension, and is dominated by several pathogenic links, the predominant is the hypertensive proteinase - angiotensin - aldosterone system, in which aldosterone is The most important hormone in this system. No specific aldosterone inhibitors have yet been found, and there are many side effects of total and subtotal adrenal glands. Therefore, people are looking for ways to increase aldosterone metabolism to lower blood pressure. Liver has the ability to inactivate induced hypertension, it is known that the blood flow through the liver once, aldosterone inactivated 90% -95%, hypertensive prostatic enzyme inactivated 20% -30%, was made experimental Surgical study aims to use the liver to eliminate pressurized substances secreted by the ischemic kidneys and to prove that renal function and liver structure are intact after “portal vein” renal and adrenal venous blood.