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在临床上应用肾上腺皮质激素(以下简称激素)治疗疾病,到现在仅有15年的历史,用激素治疗肺结核的时间更短。由于实践的时间短,积累的经验就不够丰富,因而对激素的优点和它的危害性,各个医生的看法很不一致。这样就造成了两种不合科学的做法:一种是滥用,一种是禁用。现仅就个人的临床实践体会,对激素在结核病临床应用中的几个问题,谈谈自己的看法,供同道们参考。激素在肺结核治疗上的几个发展阶段第一阶段:因为激素能减轻机体反应,促使体温下降,改善一般情况,故认为可以用它来治疗活动性肺结核。第二阶段:在用激素治疗其它疾病的过程中,发现了肺部出现新结核病灶或原有的旧结核病灶重新活动,就感到激素对肺结核是有害的。动物实验也证明:对动物先给激素以后再使它感染结核,可使肾上腺皮质功能减退,影响动物的天然免疫力,以致感染的结核病变扩散,给动物带来极为不利的影响。因此,很多医生认为以激素治疗肺结核是绝对禁忌的,激素对肺结核有害无益,在治疗任何结核病时都不能应用。
In the clinical application of adrenal cortex hormones (hereinafter referred to as hormone) treatment of disease, up to now only 15 years of history, the treatment of tuberculosis with hormone shorter time. Due to the short time of practice, accumulated experience is not rich enough, so the advantages of the hormone and its harmfulness, the views of various doctors is very inconsistent. This creates two unscientific practices: one is abuse and the other is disabling. Now only personal clinical experience, on the clinical application of hormones in tuberculosis in a few questions, to talk about their own views for the fellow reference. Hormone in the treatment of tuberculosis in several stages of development Phase 1: Because hormones can reduce the body’s reaction, promote body temperature, improve the general situation, it is considered that it can be used to treat active tuberculosis. Stage 2: Hormones are detrimental to tuberculosis when a new tuberculosis in the lungs or an old tuberculosis re-activity has been found during hormone therapy of other diseases. Animal experiments also prove that giving animals an infection of tuberculosis after giving hormones can make the function of adrenal cortex diminish and affect the natural immunity of animals so that the spread of infected tuberculosis will have an extremely adverse impact on animals. Therefore, many doctors believe that the hormone is absolutely contraindicated in the treatment of tuberculosis, hormones harmful to tuberculosis, in the treatment of any tuberculosis can not be applied.