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为进一步探讨静脉溶栓后冠脉再通对左室功能的有益影响,回顾性分析了88例静脉溶栓急性心肌梗塞(AMI)病人的二维超声心动图和部分病人的冠脉造影资料。根据溶栓再通标准分为再通组和未通组。在AMI发病后平均24.8±11.6天和22.9±24.4天分别进行了心超和冠造检查,观察室壁运动情况并测量左室射血分数(LVEF)。结果显示:未通组LVEF明显低于再通组,而室壁运动异常积分却显著高于再通组。左室扩大和室壁瘤的发生上,两组未发现有统计学差异。以上结果提示:AMI静脉溶栓使冠脉再通对左室功能和室壁运动障碍的改善起到有益的作用。
To further investigate the beneficial effects of coronary recanalization on left ventricular function after intravenous thrombolysis, two-dimensional echocardiography and coronary angiography data of 88 patients with AMI were retrospectively analyzed. According to thrombolytic recanalization standards are divided into recanalization group and failed group. Cardiac ultrasonography and coronary angiography were performed on average 24.8 ± 11.6 days and 22.9 ± 24.4 days after onset of AMI. Wall motion and left ventricular ejection fraction (LVEF) were measured. The results showed that: LVEF was significantly lower than the recanalization group, and abnormalities of wall motion was significantly higher than recanalization group. Left ventricular enlargement and the occurrence of aneurysm, no significant difference was found between the two groups. The above results suggest that: AMI intravenous thrombolysis so that coronary recanalization of left ventricular function and wall motion disorders play a beneficial role.