论文部分内容阅读
目的:分析乳腺癌术后放射治疗引起的肺损伤,对其相关因素进行统计分析。方法:回顾性总结新疆医科大学附属肿瘤医院2007年1月至2010年1月行乳腺癌改良根治或根治术后放射治疗的238例患者的资料,放射治疗计划采用常规+调强,照射计划总量为50Gy。通过患者复查胸片或胸部CT观察放射性肺损伤程度及结合临床症状确定放射性肺损伤的诊断。对238例患者放射治疗后发生放射性肺损伤的患者进行单因素及多因素的统计分析。结果:全组放射性肺损伤发生率为7.6%(18/238),其中未发生放射性肺损伤者220例(92.4%),多元Logistic回归分析显示手术方式、是否合并慢性阻塞性肺病为独立影响因素。结论:手术方式、是否合并慢性阻塞性肺病是影响放射性肺损伤发生的主要因素。
OBJECTIVE: To analyze the lung injury caused by postoperative radiotherapy for breast cancer and to analyze the related factors. Methods: The data of 238 patients who underwent modified or radical mastectomy for breast cancer from January 2007 to January 2010 in Cancer Hospital of Xinjiang Medical University were reviewed retrospectively. Radiotherapy plans were treated with conventional + The amount of 50Gy. The diagnosis of radiation-induced lung injury was determined by observing the extent of radiation-induced lung injury by chest radiography or chest CT. 238 patients with radiation-induced lung injury after radiotherapy patients were analyzed by single factor and multivariate statistical analysis. Results: The incidence of radiation-induced lung injury in the whole group was 7.6% (18/238), of which 220 cases (92.4%) had no radiation-induced lung injury. Multivariate logistic regression analysis showed that the operation mode and the COPD were independent influencing factors . Conclusion: The surgical method and whether or not chronic obstructive pulmonary disease is the main factor affecting the occurrence of radiation-induced lung injury.