肠易激综合征对健康相关生活质量的影响中的人种差异

• 作 者: Gralnek I.M. Hays R.D.ne A.M. 杨雪娟
• 机 构: Department of Medicine, CURED-gest. Dis. Research Center, Building 115, 11301 Wilshire Blvd., Los An
• 出 处: 世界核心医学期刊文摘(胃肠病学分册)
• 发表日期: 2005年03期
• 关键词: 肠易激综合征 生活质量 人种 评分值 普通美国人 慢性疾病患者 终末期肾病 胃食管反流 躯体功能 躯体疼痛

Goals: To compare the impact of irritable bowel syndrome (IBS) on health related quality of life (HRQOL) for non white and white IBS patients. Background: There are no reported data evaluating the HRQOL of non white persons with IBS. Study: S scores are compared between non white IBS patients (n = 166), white IBS patients (n = 707), the general US population, and patients with selected chronic diseases. Results: Of the 166 non white IBS patients included for analysis, 66 (40%) described themselves as African American, 56 (34%) as Hispanic, 25 (15%) as Asian American, 2(1%) as Native American and the remaining 17 (10%) as “other.“ Compared with white IBS patients, non white IBS patients reported similar decrements in their HRQOL after controlling for age, gender, income and education level. On all 8 SF-36 scales, non white IBS patients had significantly worse HRQOL compared with the general US population, (P < 0.001). Compared with GERD patients, non white IBS patients scored significantly lower on all SF-36 scales (P < 0.001) except physical functioning. Similarly, non white IBS patients had significantly worse HRQOL on selected SF-36 scales compared with diabetes mellitus and ESRD patients. Non white IBS patients had significantly better emotional well being than depressed patients, (P < 0.001). Conclusions: Non white IBS patients experience impairment in vitality, role limitations physical, and bodily pain. Yet overall, non white IBS patients report similar HRQOL to white IBS patients. These data provide the first detailed evaluation of the impact of IBS on HRQOL in non white IBS patients.

Goals: To compare the impact of irritable bowel syndrome (IBS) on health related quality of life (HRQOL) for non white and white IBS patients. Background: There are no reported data evaluating the HRQOL of non white persons with IBS. Study: S Results: Of the 166 non white IBS patients included for analysis, 66 (white), white IBS patients (n = 707), the general US population, and patients with selected chronic diseases. As Native American and the remaining 17 (10%) as ”other. " Compared with 40%) as an African American, 56 (34%) as Hispanic, 25 white IBS patients, non white IBS patients showed similar decrements in their HRQOL after controlling for age, gender, income and education level. On all 8 SF-36 scales, non white IBS patients had dramatic worse HRQOL compared with the general US population, ( P <0.001) Compared with GERD patients, non white IBS patients scored signifi Similarly, non white IBS patients had significantly worse HRQOL on selected SF-36 scales compared with diabetes mellitus and ESRD patients. Non white IBS patients had significantly better than well scales were compared to depressed patients, (P <0.001). Conclusions: Non white IBS patients experience impairment in vitality, role limitations physical, and bodily pain. Yet overall, non white IBS patients report similar HRQOL to white IBS patients. These data provide the first detailed evaluation of the impact of IBS on HRQOL in non white IBS patients.