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目的检测女性不孕患者生殖道感染情况,探讨女性生殖道感染与不孕的关系。方法选取2014年1月~2015年6月来我院生殖中心行IVF-ET的不孕妇女300例为不孕组,同期来院行孕前查体及健康查体的妇女150例为正常对照组。对所有患者进行阴道分泌物及宫颈分泌物的检查。结果不孕组的生殖道感染率为49.67%,正常组的生殖道感染率为26.00%,两组比较差异有统计学意义(P<0.05)。不孕组中支原体(UU)、衣原体(CT)、淋球菌(NG)、人乳头瘤病毒(HPV)及念珠菌(CA)的感染率分别为29.7%,11.3%,2.0%,8.3%,13%,正常组中上述感染率分别为15.3%,2.7%,1.3%,3.3%,11.3%,两组比较UU,CT,HPV的感染率差异有统计学意义(P<0.05),NG及CA的感染率差异无统计学意义(P>0.05)。两种及两种以上混合感染率的比较差异亦无统计学意义。结论生殖道感染可能是导致女性不孕的原因之一,不孕患者应加强对于支原体、衣原体、人乳头瘤病毒的检查。
Objective To detect genital tract infection in female infertility and to explore the relationship between female genital tract infection and infertility. Methods A total of 300 infertile women with IVF-ET infertility in our hospital from January 2014 to June 2015 were selected as the infertility group. 150 women with physical examination before physical examination and physical examination during the same period were selected as the normal control group. Vaginal secretions and cervical secretions were examined in all patients. Results Infertility group had 49.67% of reproductive tract infections and 26.00% of normal subjects. The difference between the two groups was statistically significant (P <0.05). The infective rates of UU, CT, NG, HPV and Candida were 29.7%, 11.3%, 2.0% and 8.3% respectively in infertility group, The infection rates of UU, CT and HPV in the two groups were statistically significant (P <0.05), and the infection rates in normal group were 15.3%, 2.7%, 1.3%, 3.3% and 11.3% The infection rate of CA was not statistically different (P> 0.05). There was no statistically significant difference in the rates of two or more mixed infections. Conclusion Reproductive tract infection may be one of the causes of infertility in women. Infertility patients should strengthen the examination of Mycoplasma, Chlamydia, HPV.