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作者报告两例成人在长期接受静脉内输注营养时发生了锌耗竭综合征,(Zine depletion syn-drome,ZDS),其临床和生化改变与未治疗过的婴儿肠源性肢端皮炎(简称AE)相似。这两例病人(男女各一)均因末端回肠炎(Cro-hn氏病)而行肠切除及回肠结肠或空肠结肠吻合术,其后长期靠静脉内输注以维持营养。在2个月后全身情况恶化,前额出现脂溢性皮炎样皮疹,口角、鼻腔周围和鼻腔内、耳部和眼睑见有血痂性湿疹或鳞屑性脓疱疹,肛周呈出血性糜烂伴白色串珠菌感染或为肛周红斑,女阴轻度糜烂。头皮有鳞屑,头发稀疏,枕部呈弥漫性大片脱发。后来在手指的
The authors report that Zinc depletion syn-drome (ZDS) occurred in two adults during long-term intravenous infusions and was associated with clinically and biochemically altered untreated infants with colic-derived extremity dermatitis AE). Both patients (one male and female) underwent bowel resection and ileocolonic or jejunal colon anastomosis due to Crohn’s disease (Crohn’s disease), followed by prolonged intravenous infusion to maintain nutrition. After 2 months the general condition deteriorated, the frontal seborrheic dermatitis rash, mouth, around the nose and nose, ears and eyelids see blood scaly eczema or scaly herpes, perianal hemorrhagic erosion with white Streptococcus infection or perianal erythema, female Yin mild erosion. Scalp scales, sparse hair, occipital showed diffuse large hair loss. Later in the fingers