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目的:总结在本院住院的溃疡性结肠炎(ulcerative colitis, UC)患者的临床特点、误诊情况及抗菌药使用状况,供临床参考. 方法:分析1991-01-01/2002-12-31在本院住院确诊为UC 患者的各类临床资料,比较不同病情程度分型患者的临床特点. 结果:126例UC有4.8%在病程中出现了UC的肠外表现, 16.7%患者伴有其他重要伴发病.被误诊的病例达到48.4%. 本组轻型病例占11.9%,中型占54.8%,重型占33.3%, 此三型患者在误诊例数、结肠镜下的病变分布和抗菌药使用情况方面分别具有统计学差异(P<0.05). 结论:UC患者的临床表现无特异性,导致误诊率较高,以轻型病例较容易误诊;结肠镜下的病变分布可影响UC的病情程度分型;本院趋向于对中、重型UC患者给予抗菌药辅助治疗,以甲硝唑和喹诺酮类抗菌药为主.
OBJECTIVE: To summarize the clinical features, misdiagnosis and antibacterial usage of ulcerative colitis (UC) hospitalized in our hospital for clinical reference.Methods: The clinical data of patients with ulcerative colitis (UC) from January 1991 to December 2002 were analyzed The hospital was diagnosed as UC patients of various clinical data to compare the clinical features of patients with different degree of disease.Results: 4.8% of 126 UC patients appeared during the course of parenteral UC, 16.7% patients with other important Accompanied by the disease was misdiagnosed cases reached 48.4% .The group of light cases accounted for 11.9%, 54.8% of the medium and heavy accounted for 33.3%, the three types of patients in the number of misdiagnosis, colon lesions and the use of antimicrobial agents (P0.05) .Conclusion: The clinical manifestations of patients with UC are nonspecific, leading to higher misdiagnosis rate and misdiagnosis in mild cases. The distribution of lesions under colonoscopy can influence the severity of UC. The hospital tends to be in the medium and heavy UC patients given antimicrobial agents adjuvant therapy to metronidazole and quinolone antibacterial drugs based.