大白鼠胸段脊髓横断引起后肢肌纤维萎缩的组织化学研究

• 作 者: 王振宇 于频 曹郁琦 孙凤云
• 机 构: 辽宁省锦州市卫生科学教育所
• 出 处: 中国医科大学学报
• 发表日期: 1996年05期
• 关键词: 脊髓横断 肌纤维萎缩 趾长伸肌 跖肌 比目鱼肌 肌纤维直径 中间型肌纤维 琥珀酸脱氢酶 胸段 红肌纤维

应用３０只大白鼠，于胸髓８～１０节段间横断，用琥珀酸脱氢酶的Ｎｉ－ｔｒｏ—ＢＴ法染色观察术后３，７，２０，４０和９０ｄ大白鼠的比目鱼肌、跖肌和趾长伸肌的肌纤维直径的变化。结果：术后４０ｄ各肌的肌纤维都呈现进行性萎缩，４０～９０ｄ比目鱼肌的肌纤维直径变化明显，而跖肌和趾长伸肌的肌纤维直径有较大程度的恢复。另外，比目鱼肌的红肌纤维比中间型肌纤维萎缩更明显，跖肌中白肌纤维萎缩最明显，趾长伸肌的各型肌纤维萎缩程度大致相同。提示：脊髓横断对不同功能以及这些肌肉中的不同型肌纤维的萎缩影响不同。

Thirty rats were used to transect between 8 and 10 segments of the thoracic bone. Siniperinus muscle and plantar of rats at 3, 7, 20, 40 and 90 days after operation were stained with Ni-tro-BT method of succinate dehydrogenase Muscle and toe extensor muscle fiber diameter changes. Results: Muscle fibers showed progressive atrophy on the 40th day after operation. The muscle fiber diameter of the soleus muscles varied significantly from 40 to 90 days, while the muscle fibers of the plantar and extensor digitorum significantly recovered. In addition, the soleus muscle red muscle fibers more obvious than the atrophy of the middle muscle fibers, white muscle fibers in the plantar muscle atrophy most obvious, long-to-extensor muscle fibers of various types of atrophy of about the same. Tip: Spinal transection has different effects on different functions and atrophy of different muscle fibers in these muscles.