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1 问:什么是肿瘤的免疫监视? 答:机体内坏境恒定的维持主要靠神经系统、内分泌系统及免疫系统起重要的作用。从机体内环境恒定的概念出发提出了肿瘤的免疫监视学说。具体来谈,即在癌细胞出现早期,机体的免疫系统能识别这些细胞为“非己”,并通过肿瘤免疫机制加以消灭,从体内消除,以保持机体内环境恒定。当肿瘤细胞逃脱了机体免疫系统的监视,就会在体内迅速分裂增殖,形成肿瘤。肿瘤免疫监视是以T细胞免疫为中心的,其根据是大多数癌细胞都有抗原性,这些抗原被T细胞识别后,能诱导出同种移植的免疫反应。除了T细胞外,白细胞介素-2(interleukin-2,IL-2)、干扰素(interferon,IFN)、自然杀伤细胞(natural killercell,NK)、单核-巨噬细胞等多种免疫系统均参与肿
1 Q: What is the immune surveillance of tumors? A: The constant maintenance of bad environment in the body plays an important role mainly by the nervous system, endocrine system and immune system. Starting from the concept of a constant environment in the body, the immunological surveillance theory of tumors was proposed. Specifically speaking, early in the cancer cells, the body’s immune system can recognize these cells as “non-self” and through the tumor immune mechanism to eliminate, eliminate from the body to maintain a constant body environment. When tumor cells escape the surveillance of the body’s immune system, they rapidly divide and proliferate in the body and form tumors. Tumor immune surveillance is based on T cell immunity, which is based on the antigenicity of most cancer cells. These antigens are recognized by T cells and induce an allograft immune response. In addition to T cells, many immune systems such as interleukin-2 (IL-2), interferon (IFN), natural killer cell (NK), and monocyte-macrophage Involved in swollen