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宫颈癌是常见的妇科恶性肿瘤之一,发病率仅次于乳腺癌,占女性恶性肿瘤的第二位。世界卫生组织和国际癌症研究所(WHO/IARC)早已明确人乳头瘤病毒(HPV)持续感染是宫颈癌的主要病因。高危型人乳头瘤病毒持续感染可引起宫颈癌前期病变-宫颈上皮内瘤变(CIN)与宫颈癌。对于2次以上检测HPV阳性,只有检测出属于同一基因型才能确认是持续感染。不同高危型的反复感染患CIN2、3的风险比为192,而相同高危型的持续感染,患CIN2、3的风险比显著升
Cervical cancer is one of the common gynecological malignancies, the incidence of breast cancer, accounting for the second in women with malignant tumors. WHO and the International Agency for Research on Cancer (WHO / IARC) have long established that persistent HPV infection is a major cause of cervical cancer. Persistent infection of high-risk human papillomavirus can cause cervical precancerous lesions - cervical intraepithelial neoplasia (CIN) and cervical cancer. For more than 2 tests for HPV positive, only detected to belong to the same genotype can be confirmed as persistent infection. The risk of CIN2,3 in patients with repeated infection of different high-risk types was 192, while the risk of persistent infection with the same high-risk type was significantly higher in patients with CIN2,3