论文部分内容阅读
由于药物对淋球菌耐药的发病率增加,寻找新的抗生素治疗淋球菌感染十分重要,作者报告内服Ciprofloxacin(吡哌酸类的奈啶酸衍生物)治疗男性无并发症的尿道淋病,取得根除的疗效。此药可抗革兰氏阴性和阳性细菌,且对青霉素、头孢菌素和氨基苷无交叉耐药性。经镜检、培养证实的淋球菌患者中,18例单剂量服Ciprofloxacin 250mg,治疗后一天全部镜检阴性,11例7天、7例14天培养全部阴性,26例单
Because of the increased incidence of drug resistance to Neisseria gonorrhoeae, it is important to find new antibiotics to treat Neisseria gonorrhoeae infection. The authors report oral administration of Ciprofloxacin (a derivative of nepicimicic acid) in the treatment of male urethral gonorrhea without complications Efficacy. This drug is resistant to both Gram-negative and positive bacteria and has no cross-resistance to penicillins, cephalosporins and aminoglycosides. After microscopic examination and culture confirmed gonococcal patients, 18 cases of Ciprofloxacin single-dose dose of 250mg, all negative one day after treatment, 11 cases of 7 days, 7 cases of 14 days all negative culture, 26 cases single