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Objective:To explore the clinical characteristics,surgical treatment and prognosis of nonsmall cell lung cancer(NSCLC) among elderly patients over 80 years.Methods:The clinical data,surgical methods,perioperative management,postoperative complications and prognosis of 52 NSCLC patients aged over 80 years were retrospectively analyzed.Results:Out of 52 cases, 27 had a long-term smoking history(51.9%) and 44 were with other diseases(84.6%).Lobectomy was done in 32 cases(65.4%),sub-lobectomy in 20 cases(38.5%),including pulmonary wedge resection in 16 cases(30.8%) and lung segment resection in 4 cases(7.7%).The postoperative complication rate was 44.2%(23/52);the complication rate after lobectomy was 62.5%(20/32) and that after sub-lobectomy was 25%(5/20),with significant difference between lobectomy and sublobectomy (P<0.05).Postoperative mortality was 3.8%(2/52).Pathological TNM staging:Ⅰa 27 cases(51.9%),Ⅰb 12 cases(23.1%),Ⅱa 8 cases(15.4%),Ⅱb 3 cases(5.8%) andⅢ2 cases(3.8%). The 1-,3- and 5-year survival rate after operation was 87.1%,59.8%,19.1%.The 1-,3- and 5-year survival rate was 86.0%,61.8%,21.5%in the patients after lobectomy,that was 89.0%,58.3%, 18.7%in the patients after sub-lobectomy,with no significant difference between two surgical methods(P>0.05).Conclusions:Octogenarians with NSCLC are often afflicted with comorbidity, so perioperative management is more complex.Strictly adhering to indications,surgery is still an important treatment of NSCLC patients over 80.
Objective: To explore the clinical characteristics, surgical treatment and prognosis of nonsmall cell lung cancer (NSCLC) among elderly patients over 80 years. Methods: The clinical data, surgical methods, perioperative management, postoperative complications and prognosis of 52 NSCLC patients aged over 80 Out of 52 cases, 27 had a long-term smoking history (51.9%) and 44 were other diseases (84.6%). Lobectomy was done in 32 cases (65.4%), sub-lobectomy in The postoperative complication rate was 44.2% (23/52); the complication rate after lobectomy was 62.5 (38.5%), including pulmonary wedge resection in 16 cases (30.8%) and lung segment resection in 4 cases % (20/32) and that after sub-lobectomy was 25% (5/20) with significant difference between lobectomy and sublobectomy (P <0.05) .Postoperative mortality was 3.8% (2/52). Pathological TNM staging: Ia 27 cases (51.9%), Ⅰb 12 cases (23.1%), Ⅱa 8 cases (15.4%), Ⅱb 3 cases (5.8%) and Ⅲ 2 cases (3.8%). The 1-, 3- and 5-year survival rate after operation was 87.1%, 59.8%, 19.1%. The 1-, 3- and 5-year survival rates were 86.0%, 61.8%, 21.5% in the patients after lobectomy , that was 89.0%, 58.3%, 18.7% in the patients after sub-lobectomy with no significant difference between two surgical methods (P> 0.05) .Conclusions: Octogenarians with NSCLC are often afflicted with comorbidity, so perioperative management is more complex Strictly adhering to indications, surgery is still an important treatment of NSCLC patients over 80.