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目的分析儿童幽门螺旋杆菌(HP)感染的临床特点,提高治疗水平。方法对辽河油田妇婴医院儿科2005-10-2009-10门诊收治的40例HP感染患儿,随机分成二组,观察组给予奥美拉唑+克拉霉素+阿莫西林3联2周口服用药治疗。对照组以甲硝唑口服代替克拉霉素用药,治疗时间相同,停药4周复查胃镜,RUT实验及13C-尿素呼气试验均阴性视为根除,一项或两项阳性视为未根除。结果治疗组根治率90.0%,对照组根治率70.0%,P<0.05。结论目前治疗儿童HP感染采用观察组方案临床根治率高。
Objective To analyze the clinical characteristics of children with Helicobacter pylori (HP) infection and improve the treatment level. Methods Forty infants with HP infection admitted to the Maternal and Infant Hospital of Liaohe Oilfield from October 2005 to October 2009 were randomly divided into two groups. The observation group was given omeprazole + clarithromycin + amoxicillin for 3 weeks for 2 weeks Medication. The control group with metronidazole oral instead of clarithromycin medication, the same treatment time, withdrawal 4 weeks review gastroscopy, RUT test and 13C-urea breath test negative were considered as eradication, one or two positive as not eradicated. Results The cure rate was 90.0% in the treatment group and 70.0% in the control group, P <0.05. Conclusion At present, the cure rate of children with HP infection in the observation group is high.