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长QT综合征(LQTS)是先天性疾病,容易伴发心脏猝死。β阻滞剂是首选药物,但是只能预防75～80%患者的晕厥发作,而20～25%仍有晕厥发作者是心脏猝死的高危者。本文报告1969年至1990年间前瞻性观察美、意等11个国家的85例 LQTS患者接受左侧心脏交感神经切除(LCSD)术的效果,直接与经治医师联系取得随访结果。 85例中女性占73%,62%有家族史,先天性耳聋占11%。手术时年龄为 20±13岁。首次晕厥距LCSD5.6±6.1年。LCSD分
Long QT Syndrome (LQTS) is a congenital disease, easily accompanied by sudden cardiac death. Beta blockers are the preferred drugs, but only prevent 75-80% of patients with syncope, and 20-25% of those who still have syncope is a high risk of sudden cardiac death. This article reports the results of a prospective observational study of left ventricular sympathectomy (LCSD) in 85 patients with LQTS from 11 countries including the United States and Italy in 1969-1990. The follow-up results were obtained directly by contact with the treating physician. Of the 85 women 73%, 62% had a family history, and congenital deafness 11%. The age of surgery is 20 ± 13 years old. The first faint from LCSD5.6 ± 6. 1 years. LCSD points