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目的借助数字化脑电图(DigitalEEG)易于定量分析脑电功率的优势,提高EEG间歇性闪光刺激诱发试验的临床诊断价值。方法本组共60例,男38例,女22例,年龄24～67岁。对60例常规EEG(-)的患者包括:癫痫20例、头痛20例和神经精神障碍20例进行了digitalEEG检查,在枕部01,0z和02处分别测量10s安静时和间歇性闪光刺激(IPS)5,10以及15Hz的α波绝对和相对功率。结果所有患者的α功率在IPS5,15Hz时减退,IPS10Hz时增高,其中癫痫患者表现最显著,而神经精神障碍患者最不明显。前者安静、IPS5,10,15Hz时枕中Oz所测绝对功率(μV2)、相对功率(%)分别为330±40,39.7±2.8,176±24,30.0±1.9,207±29,32.5±2.0和164±25,26.7±2.0;后者则分别为189±28,22.2±2.7,140±21,21.7±1.3,176±22,22.8±1.6和127±16,17.7±1.6。两者安静时的Oz处相对功率比较,P,t分别为9.85×10-24,22.75;2.42×10-29,32.5,差异有显著性意义(P<0.05)。结论DigitalEEG能够定量测定IPS的脑电功率谱变化,提高IPS的临床诊断价值。
Objective To quantitatively analyze the advantages of EEG by using digital EEG and to improve the clinical diagnostic value of EEG intermittent flash stimulation-induced test. Methods This group of 60 cases, 38 males and 22 females, aged 24 to 67 years. Sixty patients with routine EEG (-) underwent digitalEEG examinations in 20 patients with epilepsy, 20 with headache, and 20 with neuropsychiatric disorders. Seizures were measured on occipital sections 01, 0z and 02 at 10s of quiet and intermittent flash stimuli ( IPS) 5, 10 and 15 Hz alpha wave absolute and relative power. Results α power of all patients decreased at IPS5,15Hz and increased at 10Hz IPS, with the most significant manifestations in epilepsy patients and the least obvious in patients with neuropsychiatric disorders. The former is quiet, the absolute power (μV2) measured by Oz in IPS5, 10, 15Hz, and the relative power (%) are 330 ± 40,39.7 ± 2.8,176 ± 24,30.0 ± 1.9,207 ± 29,32.5 ± 2.0 And 164 ± 25, 26.7 ± 2.0 respectively; the latter were 189 ± 28, 22.2 ± 2.7, 140 ± 21, 21.7 ± 1.3, 176 ± 22, 22.8 ± 1.6 and 127 ± 16, 17.7 ± 1.6, respectively. When the two were quiet, the relative powers at Oz were compared, P, t respectively 9.85 × 10-24,22.75; 2.42 × 10-29,32.5, the difference was significant (P <0.05). Conclusion DigitalEEG can quantitatively measure the changes of IPS power spectrum and improve the clinical diagnostic value of IPS.