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脾肿大可由细菌、病毒、原虫和其他寄生虫引起的血液病和感染性疾病所致,也可见于免疫性和结缔组织性疾病。在病毒性疾病中,脾肿大可见于传染性单核细胞增多症、巨细胞病毒感染和病毒性肝炎等疾病;在慢性肝病如慢性活动性肝炎和肝硬变时也常可见到脾肿大。但尚未见无症状HBsAg携带者中的脾肿大报道。为此作者对HBsAg高流行区的HBsAg携带者测定了脾脏大小,
Splenomegaly can be caused by blood diseases and infectious diseases caused by bacteria, viruses, protozoa and other parasites, as well as immunological and connective tissue diseases. In viral diseases, splenomegaly can be seen in infectious mononucleosis, cytomegalovirus infection and viral hepatitis and other diseases; in chronic liver disease such as chronic active hepatitis and cirrhosis often also see splenomegaly . However, splenomegaly has not been reported in asymptomatic HBsAg carriers. To this end the authors of the HBsAg high prevalence area HBsAg carriers measured spleen size,