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目的观察甲硝唑栓联合雌激素软膏治疗老年性阴道炎的疗效。方法选取医院收治的老年性阴道炎患者90例为研究对象,随机分为观察组和对照组,每组45例。观察组采用甲硝唑栓联合雌激素软膏治疗,对照组采用雌激素软膏治疗;观察2组治疗效果、症状消失时间、不良反应发生率及复发率情况。结果观察组总有效率为97.2%,高于对照组的64.4%,差异有统计学意义(P<0.05);观察组各种症状消失时间短于对照组(P<0.05);观察组复发率低于对照组(P<0.05)。2组不良反应发生率差异无统计学意义(P>0.05)。结论雌激素软膏与甲硝唑栓联合治疗老年性阴道炎具有良好的效果,能快速改善患者各种症状,且药物不良反应少,安全性高,复发率较低,值得临床推广使用。
Objective To observe the curative effect of metronidazole suppository and estrogen ointment on senile vaginitis. Methods Ninety elderly patients with senile vaginitis admitted to our hospital were selected as study subjects and randomly divided into observation group and control group with 45 cases in each group. The observation group was treated with metronidazole suppository combined with estrogen ointment, and the control group with estrogen ointment. The therapeutic effect, the disappearance of symptoms, the incidence of adverse reactions and the recurrence rate were observed in the two groups. Results The total effective rate in the observation group was 97.2%, which was higher than that in the control group (64.4%), the difference was statistically significant (P <0.05); the disappearance time of various symptoms in the observation group was shorter than that in the control group (P <0.05) Lower than the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The combination of estrogen ointment and metronidazole suppository in the treatment of senile vaginitis has a good effect, can rapidly improve various symptoms of patients, and less adverse drug reactions, high safety, low recurrence rate, worthy of clinical promotion and use.