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目的探讨阴道镜下宫颈活检诊断宫颈上皮内瘤变(CIN)2/3与锥切标本的病理学结果的一致性。方法回顾性分析182例阴道镜下多点活检结果为CIN2/3行宫颈环形电切术(LEEP)或冷刀锥切术患者的临床病理资料。结果在87例CIN2患者中,LEEP锥切术后病理结果:炎症12例,CIN1 19例,CIN2 48例,CIN3 8例,符合率为55.17%(48/87);在95例CIN3患者中,冷刀锥切术后病理结果:炎症10例,CIN211例,CIN3 68例,宫颈浸润癌6例,符合率为71.58%(68/95)。结论重度宫颈上皮内瘤变患者的宫颈活检诊断与宫颈锥切术后病理结果存在一定的差异,必要时术前应进行诊断性锥切。
Objective To investigate the consistency of colposcopic biopsy in the diagnosis of cervical intraepithelial neoplasia (CIN) 2/3 and conization specimens. Methods A retrospective analysis of 182 cases of colposcopy biopsy results for CIN2 / 3 cervical ring resection (LEEP) or cold knife conization in patients with clinical and pathological data. Results In 87 CIN2 patients, the pathological results of conization of LEEP were 12 cases of inflammation, 19 cases of CIN1, 48 cases of CIN2 and 8 cases of CIN3, the coincidence rate was 55.17% (48/87). Among 95 cases of CIN3, Pathological results after cold knife conization: 10 cases of inflammation, CIN211 cases, CIN3 68 cases, 6 cases of invasive cervical cancer, the coincidence rate was 71.58% (68/95). Conclusion There are some differences between cervical biopsy in patients with severe cervical intraepithelial neoplasia and those after cervical conization. Diagnostic conization should be performed preoperatively if necessary.