论文部分内容阅读
DN 在糖尿病并发症中发生率最高,临床征象多样,病因不明。作者就DN 之血管病因及PGE_1药理和临床疗效作了探讨。据报告,多数病例腓神经活检发现神经内小血管壁有PAS 染色阳性物质沉着,内膜肥厚,腔径狭窄,肾病或视网膜病有相同之微血管病变。现已被认为,除特殊DN 病型外,是糖尿病特有的代谢障碍之基础。电镜发现,远端对称性多神经病变,其神经毛细血管内皮细胞增生,
DN in the highest incidence of diabetic complications, clinical signs and diverse, the etiology is unknown. The author of the vascular causes of DN and PGE 1 pharmacological and clinical efficacy were discussed. It has been reported that in most cases, peroneal nerve biopsy revealed the presence of PAS staining-positive substances in the inner small blood vessel walls, with the same microangiopathy as intimal hypertrophy, stenosis, nephropathy or retinopathy. Has now been considered, in addition to a special type of DN, diabetes mellitus is the basis of the unique metabolic disorders. Electron microscopy found that distal symmetrical polyneuropathy, the proliferation of neural capillary endothelial cells,