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目的探讨顺铂腹腔灌注化疗联合热疗治疗晚期卵巢上皮癌的疗效。方法晚期卵巢上皮癌患者66例,随机分为A组(34例)及B组(32例)。两组均采用顺铂腹腔灌注化疗,其中A组联合微波热疗治疗,比较两组治疗效果和不良反应的发生情况。结果 A组总有效率显著高于B组,差异具有统计学意义(P<0.05);两组患者治疗期间不良反应发生情况比较,差异无统计学意义(P>0.05)。结论顺铂腹腔灌注化疗联合微波热疗较单纯化疗效果更理想,且不增加不良反应,具有更高的临床使用价值。
Objective To investigate the efficacy of cisplatin combined with intraperitoneal chemotherapy in the treatment of advanced ovarian cancer. Methods 66 patients with advanced epithelial ovarian cancer were randomly divided into group A (34 cases) and group B (32 cases). Both groups were treated with cisplatin intraperitoneal perfusion chemotherapy, in which group A combined with microwave hyperthermia treatment, the treatment effect and adverse reactions were compared between the two groups. Results The total effective rate in group A was significantly higher than that in group B, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions during treatment (P> 0.05). Conclusion Intraperitoneal cisplatin combined with microwave hyperthermia is more effective than simple chemotherapy, and does not increase the adverse reactions, and has a higher clinical value.