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目的研究经显微镜下鼻蝶垂体瘤切除术的方法及其临床效果。方法选取本院2010.01-2011.12期间耳鼻喉科收治的垂体瘤患者40例,均在全麻下行显微镜下鼻蝶垂体瘤切除术,观察术后主要临床症状消失情况,总结术后并发症。结果所有患者均顺利进行手术,术后随访显示,临床症状恢复情况为:视力减退78.3%,肢端肥大及肥胖100%,激素异常93.0%,术后共发生尿崩3例,占比7.5%。结论经鼻蝶垂体瘤切除术术野清晰,瘤体成功切除率较高,手术具有微创性且并发症少,患者术后容易恢复,是一种高效、安全的术式。
Objective To study the method and clinical effect of microsurgical excision of pituitary tumors of the nose. Methods Forty patients with pituitary adenoma who underwent otolaryngology in our hospital from January 2010 to December 2011 were selected under general anesthesia for resection of the pituitary tumor under the microscope. The disappearance of the main clinical symptoms was observed and the postoperative complications were summarized. Results All patients underwent surgery successfully. Postoperative follow-up showed that the recovery of clinical symptoms were as follows: visual acuity 78.3%, acromegaly 100%, hormone abnormal 93.0%, and postoperative diabetes insipidus 3 cases (accounting for 7.5% . Conclusions The operation of the transsphenoidal pituitary adenoma resection has a clear operative field, a high success rate of tumor resection, minimal invasiveness and fewer complications, and is easy to recover after operation. It is an efficient and safe procedure.