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目的:探讨鼻渊康口服液的抗炎、解热和体外抑菌作用。方法:观察鼻渊康口服液对二甲苯所致小鼠耳廓炎症的影响,对大鼠棉球肉芽肿增生的影响,对细菌内毒素所致家兔体温升高的抑制作用,对金黄色葡萄球菌、表皮葡萄球菌、乙型溶血性链球菌、绿脓杆菌的体外抑制作用。结果:鼻渊康口服液对二甲苯所致小鼠耳廓炎症及小鼠腹腔毛细血管通透性增加有明显抑制作用,对大鼠棉球肉芽肿增生亦有明显抑制作用,此外,还对细菌内毒素所致家兔体温升高有抑制作用,对前述4种细菌有不同程度抑制作用。结论:鼻渊康口服液具有抗炎、解热和抑菌作用。
Objective: To explore the anti-inflammatory, antipyretic and antibacterial effects of Biyuankang Oral Liquid. Methods: To observe the effect of BiYangKang oral liquid on auricular inflammation in mice induced by xylene, the effect on the proliferation of cotton granuloma in rats, and the inhibitory effect on the increase of body temperature in rabbits caused by bacterial endotoxin. Staphylococcus, Staphylococcus epidermidis, Hemolytic Streptococcus, Pseudomonas aeruginosa in vitro inhibition. RESULTS: Biyuankang Oral Liquid significantly inhibited the auricular inflammation in mice induced by xylene and the increase of capillary permeability in the abdominal cavity of mice. It also had a significant inhibitory effect on rat granulomatous proliferation of cotton balls. Bacterial endotoxin-induced increase in rabbit body temperature has an inhibitory effect on the above four kinds of bacteria. Conclusion: Biyuankang oral liquid has anti-inflammatory, antipyretic and antibacterial effects.