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垂体泌乳素微腺瘤合并妊娠一例太原钢铁公司职工医院(030009)宋爱国患者女,35岁。婚后5年未孕,1986年开始逐渐出现头痛、溢乳、月经量减少,视物重叠、视野缺损,CT检查确诊为垂体微腺瘤,血泌乳素27.8ng/L。经服溴隐停2.5mg每日一次,四个月后妊娠,妊娠后继续服溴隐停1.25mg每日一次、一个月,孕期顺利,头痛、溢乳间断出现,无加重。1987年8月25日临产,因头盆不称,剖宫分娩一女婴,重3300克,评10分,外观无畸形,母乳喂养,产后仍口服溴隐停3.75mg每日一次,血泌乳素正常,除偶有泌乳外,症状消失。讨论:垂体腺瘤患者正常妊娠后,垂体体积和重量均增加,故可能使患者出现并发症,严重者垂体卒中。故妊娠合并垂体腺瘤孕妇应按高危妊娠监护,早期每周测HCG一次,妊34周后定期测E3,估计胎盘功能。注意有无肿瘤增长症状和体征,定期复查血泌乳素,这样可使早期并发症得到及时处理。对于患者,产后仍需监护,产后一个月全面复查。如症状改善不满意,垂体微腺瘤明显增大者,可继续治疗。垂体泌乳素微腺瘤合并妊娠一例@宋爱国$太原钢铁公司职工医院
Pituitary prolactinoma microadenoma with pregnancy case Taiyuan Iron and Steel Company Workers Hospital (030009) Song Aiguo patients Female, 35 years old. 5 years after marriage is not pregnant, gradually began in 1986, headache, galactorrhea, menstrual flow reduction, visual overlap, visual field defect, CT examination diagnosed as pituitary adenoma, prolactin 27.8ng / L. Bromocriptine 2.5mg once daily, four months after pregnancy, bromocriptine continue to take 1.25mg once a day after pregnancy, a month, a smooth pregnancy, headache, galactorrhea intermittent, no increase. August 25, 1987 labor, due to the first basin is not known, cesarean section delivery of a baby girl weighing 3300 grams, rated 10 points, the appearance of no deformity, breastfeeding, postpartum is still oral bromocriptine 3.75mg once a day, blood Prolactin normal, except occasional lactation, the symptoms disappear. Discussion: Pituitary adenoma patients after normal pregnancy, pituitary volume and weight are increased, it may make patients with complications, severe pituitary apoplexy. Therefore, pregnant women with pituitary adenoma should be at high risk of pregnancy monitoring, early detection of HCG once weekly, 34 weeks after pregnancy regularly measured E3, estimated placental function. Note the presence of tumor growth symptoms and signs, regular review of blood prolactin, so that early complications can be promptly addressed. For patients, still need custody postpartum, a full month postpartum review. As symptoms are not satisfied with the improvement of pituitary adenoma was significantly increased who can continue treatment. Pituitary prolactinoma microadenoma with pregnancy in a case @ Song Aiguo Taiyuan Iron and Steel Company Workers Hospital