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目的：调查肺间质纤维化人群中抑郁的发病率，并探讨肺纤维化并抑郁障碍发生的相关因素。方法有抑郁障碍的患者设定为观察组，未发生抑郁障碍的患者设定为对照组，采用艾森克人格问卷及社会支持量表进行调查研究，对肺纤维化伴抑郁障碍的相关因素进行分析。结果抑郁障碍的发病率为31.40%，其发生与性别、年龄、病程长短无明显相关性( P>0.05)，与社会支持、个性特征等心理社会因素等方面密切相关( P<0.05)。结论肺间质纤维化伴抑郁障碍的发病率较高，发病原因与心理社会因素密切相关。“,”Objective To investigate the incidence of depressive disorder in pulmonary fibrosis patients, and to explore the related factors with depressive disorders of pulmonary fibrosis associated. Methods observation group and control group. Investigate using Eysenck Personality Questionnaire (EPQ), medical coping mode questionnaire(MCMQ) and Social Science Research Solutions(SSRS), and analys the statistical of data between the two groups. Result The incidence of depression of pulmonary fibrosis group was 31.40%. There was closely correlation withsocial support, disease coping pattern, the personality characteristics (P<0.05). Conclusion The incidence of depressive disorder in pulmonary fibrosis patients is higher, and the depressive disorder is closely related to psychological social factors.