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据1987年《临床药学杂志》刊登肯勒思等(Kenneth I. et a1)的文献报道:1985～1986年美国FDA批准的新药共46种(1985年26种,1986年20种),其中化学药物43种,生化制剂3种。这46种新药中按FDA分级,属于1A级(有重要治疗效果)4种,1B级(中等治疗效果)24种,1C级(治疗效果差)16种,还有两种生化制剂没有分级。这46种新药中有9种是非系列型药物。从这46种新药中看到美国新药发展的趋势;以抗感染药物(9种,占19.6％);心血管药物(8种,占17.4％);镇痛抗炎药
According to Kenneth I. et al, published in the 1987 edition of the Journal of Clinical Pharmacy, 46 new drugs (26 species in 1985 and 20 species in 1986) were approved by the FDA from 1985 to 1986, among which, chemical 43 kinds of drugs, 3 kinds of biochemical preparations. Among the 46 new drugs, they were classified according to FDA and classified into 4 categories of Grade 1A (with significant therapeutic effect), 24 of Grade 1B (moderate therapeutic effect), and 16 of Grade 1C (poorly treated), and two biochemicals were not graded. Nine of the 46 new drugs are non-series drugs. From these 46 kinds of new drugs, we can see the trend of new drug development in the United States. Anti-infectives (9 species, 19.6%), cardiovascular drugs (8 species, 17.4%), analgesic and anti-inflammatory drugs