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目的明确慢性阻塞性肺疾病(COPD)患者合并医院获得性肺炎(HAP)易患因素,为COPD合并HAP提供有效防治手段。方法对确诊为COPD合并HAP的238例患者的临床资料进行回顾性分析。结果COPD合并HAP的患者,与老龄以抵抗力低下、不合理使用抗生素、住院时间长、反复行有创操作、免疫抑制剂应用指征较宽等因素相关。结论尽量减少诱发因素及提高病原学诊断水平,是防治COPD合并HAP的关键。
Objective To clarify the risk factors associated with hospital acquired pneumonia (HAP) in patients with chronic obstructive pulmonary disease (COPD) and to provide effective prevention and treatment measures for COPD combined with HAP. Methods The clinical data of 238 patients diagnosed as COPD with HAP were analyzed retrospectively. Results Patients with COPD complicated with HAP were associated with aging with low immunity, unreasonable use of antibiotics, long hospital stay, repeated invasive operation and wider application of immunosuppressive agents. Conclusions Minimizing the predisposing factors and increasing the level of pathogenic diagnosis is the key to prevention and treatment of COPD with HAP.