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本文研究不同程度缺氧条件下,肺癌A5 4 9细胞内过氧化物酶体增殖的激活受体α(PPARa)和缺氧诱导因子1α(HIF - 1α)的表达状况,及反义封闭HIF - 1α后,对PPARa表达的影响,以了解PPARa和HIF - 1α的相关性。作者将A5 4 9细胞分为4组:对照组(A组)在5 %CO2 培养箱中37℃培养。将细
In this paper, we investigated the expression of peroxisome proliferator activated receptor α (PPARa) and hypoxia - inducible factor 1α (HIF - 1α) in lung cancer A549 cells under hypoxia and antisense blocking HIF - 1α on the expression of PPARa in order to understand the correlation between PPARa and HIF - 1α. The authors divided A549 cells into 4 groups: control group (Group A) was cultured in a 5% CO2 incubator at 37 ° C. Will be fine