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目的研究女性患者颈部动脉粥样硬化与性激素水平的相关性。方法选择2013年5月—2014年6月进行检查的绝经后女性253例,经B超筛查出有斑块患者58例及无斑块患者56例,将其中诊断结果为有斑块的58例患者组成观察组,其中无斑块的56例患者组成对照组。观察组又分为轻度组23例,中度组19例,重度组16例。观察所有患者的性激素水平情况及血脂和血纤维蛋白原情况变化。结果通过检查发现,观察组患者的激素水平明显低于对照组,有统计学意义(P<0.05),观察组中以中重度组颈部动脉粥样硬化斑块性激素水平最低,与轻度组动脉粥样硬化斑块性激素水平相比,有统计学意义(P<0.05)。观察组患者血脂和血纤维蛋白原也与对照组有统计学意义(P<0.05)。结论性激素水平与女性患者颈部动脉粥样硬化有明显关系,能有效的判断女性患者是否患有颈部动脉粥样硬化斑块,临床医生可以将性激素水平作为判断颈部粥样硬化的重要指标。
Objective To investigate the relationship between cervical atherosclerosis and sex hormone levels in female patients. Methods A total of 253 postmenopausal women were selected from May 2013 to June 2014. Fifty-eight patients with plaque and 56 patients without plaque were identified by B-mode ultrasonography. Fifty-eight of them were diagnosed as having plaque The patients were grouped into observation group, of which 56 patients without plaque formed the control group. The observation group was divided into mild group of 23 cases, moderate group of 19 cases, severe group of 16 cases. All patients were observed sex hormone levels and changes in serum lipids and fibrinogen. Results The examination showed that the hormone levels in the observation group were significantly lower than those in the control group (P <0.05). In the observation group, the level of atherosclerotic plaque was the lowest in the moderate and severe groups, The levels of sex hormones in atherosclerotic plaque were statistically significant (P <0.05). The level of serum lipids and fibrinogen in the observation group was also significantly higher than that in the control group (P <0.05). Conclusions The level of sex hormones has a clear relationship with cervical atherosclerosis in female patients. It can effectively determine whether female patients have cervical atherosclerotic plaque. Clinicians can use sex hormone levels as an important index to judge neck atherosclerosis .