Immunomodulatory approaches to CNS injury:extracellular matrix and exosomes from extracellular matri

• 作 者: Yolandi van der Merwe Michael B.Steketee
• 机 构: Department of Bioengineering,Swanson School of Engineering,University of Pittsburgh,Department of Op
• 出 处: Neural Regeneration Research
• 发表日期: 2016年04期
• 关键词: macrophages neuronal degeneration innate permanent conditioned remodeling phenot

After central nervous system(CNS)injury,a pro-inflammatory,innate immune response contributes to permanently lost neuronal function by promoting changes in the micro-environment and extracellular matrix(ECM)that lead to CNS neuronal degeneration and death and permanent scarring.This pro-inflammatory immune

After central nervous system (CNS) injury, a pro-inflammatory, innate immune response contributes to permanently lost neuronal function by promoting changes in the micro-environment and extracellular matrix (ECM) that lead to CNS neuronal degeneration and death and permanent scarring. pro-inflammatory immune