龈沟液天门冬氨酸氨基转换酶定性与定量试验的对比研究

• 作 者: 沙月琴 曹采方 栾庆先 耿素芳 李晓新
• 机 构: 北京医科大学口腔医学院!100081,北京医科大学口腔医学院!100081,北京医科大学口腔医学院!100081,北京医科大学口腔医学院!100081,北京医科大学口腔医学院!100081
• 出 处: 北京医科大学学报
• 发表日期: 2004年期
• 关键词: 龈沟液 牙周组织 渗出物／酶学 牙周健康 定性检测 牙周炎／诊断 牙周炎患者 过筛试验 定量试验 试剂盒

目的：评价牙周组织监测试剂盒（PTM）对龈沟液天门冬氨酸氨基转换酶（GCF-AST）定性检测的临床应用价值。方法：用PTM试剂盒进行定性检测，用天门冬氨酸氨基转换酶的常规方法进行定量检测。结果：牙周健康者全为阴性，牙龈炎者63．75％为阳性；定性对定量试验的灵敏度为72．03％，特异度为64．71％，调整一致率为66．08％。结论：PTM为一种简便、快速的过筛试验，可用来反映牙周组织的破坏状况。

Objective: To evaluate the clinical value of periodontal tissue monitoring kit (PTM) in the qualitative detection of GCF-AST in gingival crevicular fluid. Methods: Qualitative detection with PTM kit, aspartate aminotransferase by conventional methods for quantitative detection. Results: All patients with periodontal health were all negative, with 63.75% of gingivitis as positive. The sensitivity of qualitative test to quantitative test was 72.03%, the specificity was 64.71% and the consistency of adjustment was 66.08%. Conclusion: PTM is a simple and rapid screening test that can be used to reflect the destruction of periodontal tissue.