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目的了解丙型肝炎病毒(HCV)在山东省艾滋病病毒(HIV)感染者中的感染状况,分析HIV、HCV共感染者的流行病学特征。方法对2000-2010年底,山东省报告的HIV感染者/艾滋病(AIDS)病人确证时的血样进行HCV检测,选取现在存活的、年龄≥18岁的HIV感染者和AIDS病人为研究对象,通过研究对象HIV确证后的首次随访调查表,收集流行病学信息,进行单因素分析和多因素Logistic回归分析。结果 HIV与HCV共感染率为41.7%(842/2 021)。单因素分析发现,不同文化程度、不同性别、籍贯和传染途径、不同民族之间差异有统计学意义(P<0.05),在此基础上进行多因素的Logistic回归分析发现,性别、籍贯和感染途径是HIV/HCV共感染的独立危险因子。结论不同性别、籍贯和传染途径中HIV、HCV共感染率不同,应引起重视。
Objective To understand the status of hepatitis C virus (HCV) infection among HIV-infected persons in Shandong Province and to analyze the epidemiological characteristics of HIV and HCV co-infected patients. Methods The blood samples of confirmed HIV / AIDS patients reported in Shandong Province from the end of 2000 to the end of 2010 were tested for HCV, and the HIV-infected and HIV-infected patients aged> 18 years who were alive were selected as study subjects. Subjects were first confirmed by HIV follow-up questionnaire to collect epidemiological information, univariate analysis and multivariate Logistic regression analysis. Results The co-infection rate of HIV and HCV was 41.7% (842/2 021). Univariate analysis showed that there were significant differences among different ethnic groups (P <0.05) according to different educational level, gender, origin and route of infection. Based on the above analysis, Logistic regression analysis showed that gender, origin and infection Pathway is an independent risk factor for HIV / HCV co-infection. Conclusions The co-infection rates of HIV and HCV in different sex, origin and route of infection are different and should be taken seriously.