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目的观察盐酸氨基酮戊酸外用散(ALA)光动力联合中药保留灌肠治疗肛管尖锐湿疣的疗效。方法将84例肛管尖锐湿疣患者随机分为两组。治疗组给予ALA光动力联合中药保留灌肠治疗;对照组给予ALA光动力治疗。比较两组的治疗有效率、复发率及不良反应发生率。结果疗程结束后治疗组有效率与对照组比较无统计学意义(P>0.05);治疗组复发率较对照组显著降低(P<0.05);治疗组不良反应发生率也较对照组显著降低(P<0.05)。结论 ALA光动力联合中药保留灌肠治疗肛管CA复发率、不良反应发生率低,优于单纯ALA光动力治疗。
Objective To observe the curative effect of aminolevulinic acid hydrochloride (ALA) photodynamic therapy combined with traditional Chinese medicine retention enema in the treatment of anal canal condyloma acuminatum. Methods Eighty-four patients with anal genital warts were randomly divided into two groups. The treatment group was given ALA photodynamic therapy combined with Chinese medicine retention enema; control group given ALA photodynamic therapy. Compare the two groups of treatment efficiency, recurrence rate and adverse reaction rate. Results The effective rate of the treatment group after the end of treatment was not significantly different from that of the control group (P> 0.05). The relapse rate of the treatment group was significantly lower than that of the control group (P <0.05), and the incidence of adverse reactions in the treatment group was significantly lower than that of the control group P <0.05). Conclusions ALA photodynamic therapy combined with traditional Chinese medicine retention enema treatment of anal canal CA recurrence rate, the incidence of adverse reactions is low, superior to simple ALA photodynamic therapy.