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一般认为乙型肝炎病毒(HBV)并不直接损害肝细胞,机体免疫应答为引起肝脏损害的重要原因。肝脏发生病变后,出现蛋白质代谢障碍及肝细胞内容物逸出,又可继发一些免疫功能障碍。补体参与机体免疫反应,且肝脏又是合成补体的重要器官,因此,完全有理由相信乙型肝炎(HB)和肝硬化(LC)患者的血清补体检测对了解病情及研究其免疫反应都有很重要的意义。但是,简便的补体检查在当前临床工作上并没有受到应有的重视。我们自1980年起系统地研究了HB和LC患者的血清经典途径和旁路途径
Hepatitis B virus (HBV) is generally believed that does not directly damage the liver cells, the immune response is an important cause of liver damage. After the occurrence of liver disease, protein metabolism and liver cell content to escape, but also secondary to some immune dysfunction. Complement involved in the immune response, and the liver is an important complement synthesis of organs, there is every reason to believe that hepatitis B (HB) and cirrhosis (LC) serum complement testing to understand the condition and to study the immune response is very Significance. However, simple and convenient complement examination in the current clinical work did not receive the attention it deserves. We have systematically studied the serum classical and alternative pathways of HB and LC patients since 1980