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目的探析奥美拉唑联合磷酸铝凝胶治疗急性酒精性胃黏膜出血的临床效果。方法 89例急性酒精性胃黏膜出血患者,按治疗方案不同分为对照组(35例)和研究组(54例)。对照组行单纯奥美拉唑治疗,研究组行奥美拉唑联合磷酸铝凝胶治疗,对比两组治疗效果以及止血时间、住院时间、输血量。结果对照组患者总有效率为77.14%,低于研究组的92.59%。两组比较差异具统计学意义(P<0.05)。对照组止血时间、住院时间以及输血量分别为(20.92±8.11)h、(7.33±2.16)d、(855.92±163.18)ml,研究组分别为(12.82±5.63)h、(4.35±1.49)d、(325.57±108.65)ml,两组患者止血时间、住院时间以及输血量比较差异具统计学意义(P<0.05)。结论奥美拉唑联合磷酸铝凝胶治疗急性酒精性胃黏膜出血的临床效果显著,值得推广。
Objective To investigate the clinical effect of omeprazole combined with aluminum phosphate gel in the treatment of acute alcoholic gastric mucosal hemorrhage. Methods Eighty-nine patients with acute alcoholic gastric mucosal hemorrhage were divided into control group (n = 35) and study group (n = 54) according to different treatment regimens. The control group was treated with omeprazole alone. The study group was treated with omeprazole and aluminum phosphate gel. The therapeutic effect, the bleeding time, length of hospital stay and blood transfusion were compared between the two groups. Results The total effective rate of the control group was 77.14%, which was lower than 92.59% of the study group. The difference between the two groups was statistically significant (P <0.05). The bleeding time, hospital stay and blood transfusion in the control group were (20.92 ± 8.11) h and (7.33 ± 2.16) d and (855.92 ± 163.18) ml, respectively, and were 12.82 ± 5.63 and 4.35 ± 1.49 d , (325.57 ± 108.65) ml respectively. There was significant difference between the two groups in the bleeding time, hospital stay and blood transfusion volume (P <0.05). Conclusion Omeprazole combined with aluminum phosphate gel in the treatment of acute alcoholic gastric mucosal bleeding is clinically significant and worth promoting.