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目的了解泌尿生殖道支原体属感染状况及对抗菌药物的耐药性。方法对医院门诊可疑非淋病性尿道炎患者853例的泌尿生殖道分泌物标本,进行支原体属培养及药敏试验。结果支原体属培养阳性率59.1%,其中,解脲脲支原体(Uu)检出率最高,占77.8%;人支原体(Mh)检出率很低,仅占2.4%;Uu+Mh感染检出率为19.8%;21~40岁年龄段患者培养阳性率最高(79.0%~79.5%);Uu药敏试验显示:Uu对环丙沙星、氧氟沙星的耐药率为79.8%、59.9%;对普那霉素敏感率最高,为100.0%;其次对多西环素、交沙霉素、四环素敏感率较高,分别为94.9%、94.1%、93.4%。结论 Uu对喹诺酮类抗菌药物已产生了严重的耐药性,临床应限制使用。
Objective To understand the infection status of genitourinary tract mycoplasma and its antibiotic resistance. Methods A total of 853 cases of genitourinary tract secretions in suspected out-patient non-gonococcal urethritis patients were tested for mycoplasma culture and susceptibility testing. Results The positive rate of Mycoplasma was 59.1%. The detection rate of Uu was the highest, accounting for 77.8%. The detection rate of M. tuberculosis was very low (2.4%). The detection rate of Uu + Mh (19.8%). The highest positive rate was found in patients aged 21-40 years (79.0% -79.5%). Uu susceptibility test showed that the drug resistance rates of Uu to ciprofloxacin and ofloxacin were 79.8% and 59.9% ; The highest sensitivity rate to pristinamycin was 100.0%; followed by sensitivity to doxycycline, jasamycin and tetracycline, 94.9%, 94.1% and 93.4% respectively. Conclusion Uu quinolone antibacterial drugs have a serious resistance, clinical use should be limited.